Just like a person, Quick Base (and all database) applications age over time. Developers add fields, reports and relationships that become obsolete, but don't clean up after themselves. Eventually, there are all kinds of database elements that no one remembers and just confuse the user. The original developers leave the organization and their successors look at the app (originally so well-conceived!) and say "who designed this mess?"
There's no fountain of youth, but there are some things you can do to avoid database sprawl.
1. Isolate the chaos